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  • Gough, A.H. and P.A. Johnston, Requirements, features and performance of high content screening platforms, in high content screening: a powerful approach to systems cell biology and drug discovery. Methods in Molecular Biology, 2006. 356: p. 41-61.
  • Williams, R.G., et al., Generation and characterization of a stable MK2-EGFP cell line and subsequent development of a high-content imaging assay on the Cellomics ArrayScan platform to screen for p38 mitogen-activated protein kinase inhibitors. Methods Enzymol, 2006. 414: p. 364-89.
  • Trask, O.J., Jr., et al., Assay development and case history of a 32K-biased library high-content MK2-EGFP translocation screen to identify p38 mitogen-activated protein kinase inhibitors on the ArrayScan 3.1 imaging platform. Methods Enzymol, 2006. 414: p. 419-39.
  • Nickischer, D., et al., Development and implementation of three mitogen-activated protein kinase (MAPK) signaling pathway imaging assays to provide MAPK module selectivity profiling for kinase inhibitors: MK2-EGFP translocation, c-Jun, and ERK activation. Methods Enzymol, 2006. 414: p. 389-418.
  • Madiraju, C., et al., Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin. Biochemistry, 2005. 44: p. 15053-63.
  • Vogt, A., et al., Cell-active dual specificity phosphatase inhibitors identified by high-content screening. Chem Biol, 2003. 10: p. 733-42.
  • Vogt, A., E.N. Kalb, and J.S. Lazo, A scalable high-content cytotoxicity assay insensitive to changes in mitochondrial metabolic activity. Oncol Res, 2004. 14: p. 305-14.
  • Vogt, A. and J.S. Lazo, Chemical complementation: a definitive phenotypic strategy for identifying small molecule inhibitors of elusive cellular targets. Pharmacol Ther, 2005. 107: p. 212-21.
  • Vogt, A. and J.S. Lazo, Discovery of protein kinase phosphatase inhibitors. Methods Mol Biol, 2007. 356: p. 389-400.
  • Vogt, A. and J.S. Lazo, Implementation of high-content assay for inhibitors of mitogen-activated protein kinase phosphatases. Methods, 2007. 42: p. 268-77.
  • Vogt, A., et al., Spatial analysis of key signaling proteins by high-content solid-phase cytometry in Hep3B cells treated with an inhibitor of Cdc25 dual-specificity phosphatases. J Biol Chem, 2001. 276: p. 20544-50.
  • Vogt, A., et al., The benzo[c]phenanthridine alkaloid, sanguinarine, is a selective, cell-active inhibitor of mitogen-activated protein kinase phosphatase-1. J Biol Chem, 2005. 280: p. 19078-86.
  • Vogt, A., et al., The antisignaling agent SC-alpha alpha delta 9, 4-(benzyl-(2-[(2,5-diphenyloxazole-4-carbonyl)amino]ethyl)carbamoyl)- 2-decanoylaminobutyric acid, is a structurally unique phospholipid analogue with phospholipase C inhibitory activity. Mol Cancer Ther, 2002. 1: p. 885-92.
  • P. A. Johnston. (2007) “Automated High Content Screening Microscopy” Chapter 2, p25-42, in High Content Screening: Science, Technology and Applications. John Wiley & Sons, Inc; Edited by: Stephen A. Haney.
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